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1. Estimating the UK's Return on Investment from an Ambitious Program to Incentivize New Antibiotics

Author:
Rachel Silverman and Adrian Towse
Publication Date:
12-2022
Content Type:
Policy Brief
Institution:
Center for Global Development
Abstract:
Anti-microbial drugs form the backbone of modern medicine. Yet their lifespan is naturally limited; over time, use of these drugs selects for mutations that survive exposure those same drugs, driving “anti-microbial resistance,” or AMR. Already, drug-resistant infections kill an estimated 7,600 citizens of the United Kingdom (UK) every year. In the absence of sufficient research and development (R&D) investment for new antimicrobials, deaths from drug-resistant infections could increase dramatically in the coming decade. To address this growing crisis and solve market failures that prevent the development of new antibiotics, the UK has set up “subscription models” for purchasing antibiotics; this has been applied to two drugs thus far, and the model is under consideration for a broader rollout. In this note, we present the results of a modelling exercise to estimate the likely return on investment (ROI) from an expanded program to incentivize new antibiotics, assuming it is paired with complementary and proportionate efforts from the UK’s G7 partners. The results are necessarily imprecise due to several uncertain parameters, but nevertheless provide evidence of a very high expected ROI that is robust to different inputs and assumptions.
Topic:
Health, Science and Technology, Health Care Policy, and Medicine
Political Geography:
United Kingdom and Europe

2. UK Research Aid: Tied, Opaque and Off-Topic?

Author:
G. Lee Robinson, Euan Ritchie, and Charles Kenny
Publication Date:
07-2019
Content Type:
Research Paper
Institution:
Center for Global Development
Abstract:
The UK has considerably increased the amount of aid it spends on research in recent years. This policy follows statements by DFID that research is among the best ways of spending aid. It also follows the UK legislating a commitment to spend 0.7 percent of GNI as foreign aid. In pursuing this target, the UK has decreased the proportion of bilateral aid spent through DFID and has channelled more through other departments. BEIS and the Department for Health and Social Care have been big recipients, and research accounts for much of their increased share of aid budgets. The information associated with the majority of this research aid is vague, raising questions about transparency. A large amount of the research is financed using an allocation mechanism that effectively ties it to UK institutions. There are also questions as to the poverty focus of some of the research conducted, given the explicit intention of the UK government to find existing activity to reclassify as ODA following the legislating of the 0.7 percent target. We suggest reporting reforms that will increase transparency and allow greater scrutiny of the way UK research aid is spent. We also call for the UK to live up to its reporting to the OECD that all British aid is untied.
Topic:
Health, Research, Academia, and Funding
Political Geography:
United Kingdom and Europe

3. Five Things the Health Minister Should Do to Enhance the UK’s Global Health Footprint

Author:
Kalipso Chalkidou
Publication Date:
07-2019
Content Type:
Policy Brief
Institution:
Center for Global Development
Abstract:
As Health Secretary Matt Hancock returns to his role as part of Boris Johnson’s premiership, he has an opportunity to make good on the UK’s renewed confidence and ambition by drawing on what the new prime minister calls the “best healthcare [system]” to drive improvements in health globally. The UK’s Department of Health and Social Care controls its biggest-ever official development assistance (ODA) budget, doubling between 2017 and 2018 to just under £200m, or 1.3 percent of the country’s aid allocation. This places the UK’s secretary of state for health in a unique position to truly make a difference in countries’ journeys towards universal healthcare coverage (UHC), whilst also defending (and making a case for more of) the ODA money his department has been allocated, even to development aid’s harshest critics. Here are five things he can do to make this happen, both using his own department’s ODA budget and influencing how DFID’s majority share is spent.
Topic:
Health, Governance, Health Care Policy, and Leadership
Political Geography:
United Kingdom and Europe

4. Strengthening European Leadership on Global Health Security

Author:
Amanda Glassman, Jeremy Konyndyk, and Liesl Schnabel
Publication Date:
10-2019
Content Type:
Policy Brief
Institution:
Center for Global Development
Abstract:
Impending leadership transitions in EU institutions provide a unique opportunity to bolster European action on global health security. This would be a double win for the EU: advancing its efforts to foster progress in developing countries while also protecting Europe itself against potential disease risks. To help strengthen the EU’s leadership on global health security, the new Commission should
Topic:
Security, Health, Regional Cooperation, European Union, and Leadership
Political Geography:
Europe